Discussion on the action mechanism of nano zinc oxide in sterilization

Nanotechnology and nano materials have been applied to all aspects of life. For example, nano titanium dioxide can be used in sunscreen cosmetics, nano zinc oxide can be used in surface coating products of space shuttles, and nano materials such as ceramics and rubber industry have been studied in industry. At present, the research of nano carriers and nano drugs has attracted the attention of researchers, and nano materials are gradually used in the medical field. Nanometer zinc oxide is a new high-performance micro inorganic material facing the 21st century. Its particle size is about 1~100nm, so let's talk about the action mechanism of nano zinc oxide in sterilization!


Discussion on the action mechanism of nano zinc oxide in sterilization


Nanometer zinc oxide can be used for sterilization in the pharmaceutical industry. Its mechanism can be divided into three aspects:

On the one hand, when the cells react with groups with proteins, they destroy the spatial structure of bacteria and proteins in cells, inactivating protease in cells and killing bacteria. After destruction, nano zinc oxide can continuously release zinc ions in the water medium, zinc ions enter the cell membrane, destroy the cell membrane, zinc ions free from bacteria, and repeat the sterilization process.

Second, nano zinc oxide interacts with bacterial surface cell wall to destroy bacterial cell wall and release contents to kill bacteria.

Third, under the irradiation of ultraviolet light, the water or hydroxyl adsorbed on the surface is converted into hydroxide free radicals, and the oxygen adsorbed is converted into active oxygen. Nanometer zinc oxide produces hole electron pairs. The electrons and holes move from the conduction band and the valence band to the surface of zinc oxide particles respectively. When the particle size of nano zinc oxide is too small, the time for electrons and holes to reach the crystal surface from the conduction band and the valence band is greatly shortened. Hydroxide free radicals and reactive oxygen species have strong chemical activity and can react with many organic substances to kill many bacteria and viruses. The probability of hole and electron recombination is also reduced.

In addition, the bactericidal effect of nano zinc oxide combined with other aspects of performance, there are other uses.

1. Production of surgical clothes

Nanometer zinc oxide has the function of shielding ultraviolet light due to its absorption and scattering of ultraviolet light. When receiving ultraviolet radiation, valence band electrons can absorb the energy of ultraviolet radiation and migrate to the conduction band. After migration, hole electron pairs are generated and ultraviolet radiation is also absorbed. In addition, because nano zinc oxide is a direct band gap semiconductor, when the wavelength of ultraviolet light is larger than the particle size of nano zinc oxide, nano particles can make medium and long wavelength ultraviolet light scatter in all directions, reducing the intensity in the direction of ultraviolet radiation.

2. Application in dentistry

The composite resin used for early dental treatment is not strong enough, and treatment often fails, resulting in mixed resin with good performance. In addition, the solid quadrangle can isotropically change the mechanical properties of the material. When it is added to the composite resin system, the nano zinc oxide crystal structure is complete, almost without internal defects, and has the characteristics of high strength and high modulus, which can significantly improve the mechanical properties of the composite resin. In addition, it can be used in dental resin instead of traditional porcelain baked teeth.

The above is a brief introduction to the action mechanism of nano zinc oxide in sterilization. If you need to know more, please contact us at any time!